In 1978, a 17-year-old Yann LeCun was told by his math teacher that he wasn't cut out for France's most elite schools.

Instead, he enrolled in engineering school ESIEE PARIS to study electrical engineering. A perfectly respectable career.

Then he picked up a book.

In 2016, Niki Parmar had no PhD, no formal research title, and no one asking her to co-author what would become the most cited AI paper of the 21st century.

At Google, a small research team was trying to figure out how to make AI understand language faster. They had a radical idea: what if AI could read an entire sentence at once, instead of one word at a time?

Niki wasn't supposed to be central to that effort. The youngest on her team, she was a software engineer from Pune, India who had first learned AI through free online courses in college.

In 2022, Aravind Srinivas sat outside Yann LeCun's office for five hours with no appointment.

LeCun was a Turing Award winner, one of the "Godfathers of AI," and a professor at NYU.

Srinivas was a 28-year-old with a prototype for an AI search engine held together with conviction.

In 2012, Andrew Ng launched Coursera to bring world-class education to millions. The first power user is his 66-year-old father.

Dr. Ronald Ng was a hematologist in Singapore. When his son's platform went live, he signed up for a logic course from the University of Michigan.

He got hooked.

In 2001, a 26 year old engineer named John Ternus stood in a supplier's factory late at night, holding a magnifying glass over a tiny screw.

It was his first project at Apple: a desktop monitor called the Cinema Display.

The back panel screws were supposed to have 25 grooves on their heads. The supplier had cut 35. Ternus wouldn't let it go.

In 2011, John Jumper started a chemistry PhD at the University of Chicago. He had never taken a college chemistry class in his life.

He wanted to pursue a PhD in physics, but he had missed Chicago's application deadline by hours. The department wouldn't let him apply late.

When someone suggested a PhD in chemistry, he said: "sure, how hard can this be?" He was accepted.

In 1990, Jeff Dean studied neural networks and said: "give me 32 more computers and I can make this work." He was directionally correct. He just needed 15,968 more.

Dean was a 21-year-old senior at the University of Minnesota, training neural networks on the CS department's beefiest machine. He believed in its potential. The hardware just hadn't caught up yet.

So he filed it away. In 1999, he joined Google as its 30th employee and spent the next decade scaling search with Sanjay Ghemawat, writing the systems that would become the backbone of the modern internet.

In 2008, Satya Nadella made a phone call that would cost him his own job title.

At that time, Nadella was a 16-year Microsoft veteran and an SVP running R&D for the search division.

The person on the other end of the call was Qi Lu, a computer scientist who had spent a decade at Yahoo managing 3,000 engineers.

In 1995, Katalin Karikó was given a choice by her university: stop researching mRNA, or accept a demotion and pay cut.

Most scientists had already abandoned mRNA research. It triggered dangerous immune reactions. Grant committees called it impractical.

The safe move was obvious: Pivot to something fundable. Chase the grants. Rebuild her career.

In 2016, Tony Xu told investors DoorDash wouldn't compete in New York. Or San Francisco. Or any major city.

He was sending DoorDash to the suburbs. They thought he was crazy.

Xu grew up washing dishes beside his mother in a Chinese restaurant in Champaign, Illinois. His family had immigrated from China with a few hundred dollars. McDonald's was a luxury.